Published:Journal of Chromatographic Science,
ISSN 0021-9665 Volume
48, Number 1, January 2010, pp. 18-21
Applications of Ultra-Performance Liquid Chromatography
to Traditional Chinese Medicines
Gui-Ling Yang1, Li-Wei Yang2, Yong-Xue
Li2, Hui Cao1,
Wen-Liang Zhou1, Zhi-Jian Fang3, Hong-Bo Zhou3,
Jie-Li Mo2, Shu-Xiong
Xiao2, and Hui-Rong Lin2
1School of Life Science, Sun Yat-Sen University, Guangzhou, 510275,
China;
2Guangdong Institute for Drug Control, Guangzhou, 510180, China;
3Guangdong Pharmaceutical University, 510006, China
Ultra-performance liquid chromatography (UPLC),
as a development of the chromatographic technique, was used in
the quality control of Panax ginseng C.A. Mey. In the study,
the UPLC methods were transferred from conventional high-performance
liquid chromatography (HPLC) methods according to chromatographic
equations. The results demonstrated that UPLC analysis methods
could be transferred from HPLC without loss of efficiency. Compared
with conventional HPLC, UPLC made a surprising 10-fold increase
in speed and 20-fold decrease in solvent consumption. The study
indicated UPLC as a suitable alternative to HPLC and can be reliably
applied to quality control of traditional Chinese medicines.
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