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Published:Journal of Chromatographic Science,
ISSN 0021-9665 Volume
47, Number 5, May/June 2009, pp. 354-358
Separation of Cyclosporins and Other Antibiotics
by HSCCC
Wei Zheng
Fujian Provincial Key Laboratory of Screening for Novel Microbial
Products, Fujian Institute of Microbiology, Fuzhou, P.R. China,
350007
Applications of high-speed counter-current chromatography
(HSCCC) for the separations of antibiotics, cyclosporins and
isoflavones, by a marine Micromonospora and macrolides
including tacrolimus, ascomycin, and dihydroFk-506 are described.
The application of silver ion HSCCC technique in the separation
of tacrolimus from its components is also described.
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