Published:Journal of Chromatographic Science,
ISSN 0021-9665 Volume
47, Number 8, September 2009, pp. 689-693
Optimization of a Novel Procedure for Determination
of VOCs in Water and Human Urine Samples Based on SBSE Coupled
with TD-GC–HRMS
Natalia Jakubowska1, Bernhard Henkelmann2,
Karl-Werner Schramm2, and Jacek Namiesnik3
1Department of Analytical Chemistry, Chemical Faculty, Gda´nsk University
of Technology (GUT), 11/12 G. Narutowicza Street, 80-952 Gdansk, Poland;
2Helmholtz Zentrum München, Institute of Ecological
Chemistry, Ingolstaedter Landstr. 1, D-85764 Neuherberg, Germany; and
3Gdansk University of Technology, 80-233 Gdansk
In this study, stir-bar sorptive extraction and
thermal desorption followed by gas chromatography coupled with
high resolution mass spectrometry was applied for determination
of halo-organic compounds (bromodichloromethane, dibromochloromethane,
bromoform, and tetrachloroethylene) in water and human urine
samples. Time of extraction and stirring speed were optimized.
The results show that the optimum extraction time is 30 min with
600 rpm of stirring speed with Twister of 20 mm in length and
1.0-mm film thickness of PDMS (126 µL). The calibration
curves, limits of detection and quantification for all compounds
were calculated. This procedure is characterized by very low
limits of detection and quantitation: lower than 0.0017 µg/L
and good repeatability for all four volatile compounds. This
new analytical procedure was identified to be easy, reliable,
sensitive, and requires only small amounts of sample. It can
constitute a good alternative to well-known procedures based
on application of head space and gas chromatography coupled with
electron capture detection.
Reproduction
of editorial content of this journal is prohibited without publisher’s
permission.
This
article is available in its entirety by fax for $4.00 per
page.
Visa or MasterCard accepted. To
order electronically
click here
or call: 847-647-2900 ext. 1323
or fax request to: 847-647-1155.
Please
indicate JCS volume and issue along with
page numbers. |
Site Map: Home
| Current Issue | Subscribe
| Back Issues | About
Us | Meetings | Advertising
|
| Books for Sale | For
the Author | Links | Supplier
Info | Search | |
|
