Published:Journal of Chromatographic Science,
ISSN 0021-9665 Volume
46, Number 3, March 2008, pp. 233-247
Determination Methods for Biologically Active
Compounds by Ultra-Performance Liquid Chromatography Coupled
with Mass Spectrometry: Application to the Analyses of Pharmaceuticals,
Foods, Plants, Environments, Metabonomics, and Metabolomics
Toshimasa Toyo’oka
Division of Bio-Analytical Chemistry, School of Pharmaceutical
Sciences, and Global COE Program, University of Shizuoka, 52-1
Yada, Suruga-ku, Shizuoka 422-8526, Japan
This review summarizes the determination methods
for biologically active compounds, such as pharmaceuticals, agrochemicals,
and biogenic amines, by ultra-performance liquid chromatography
coupled with mass spectrometry. The typical applications using
the method are also described in this study, together with the
characteristics of the methods.
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