Published:Journal of Chromatographic Science,
ISSN 0021-9665 Volume
45, Number 9, October 2007, pp. 559-577
Capillary Electrophoresis in Pharmaceutical Analysis:
A Survey on Recent Applications
Leena Suntornsuk
Faculty of Pharmacy, Mahidol University, 447 Sri-Ayudhaya Rd.,
Rajathevee, Bangkok 10400 Thailand
Capillary electrophoresis (CE) has a significant
role in drug discovery and manufacturing processes and has a
potential to grow further, due to new developments that can provide
highly sensitive and high throughput analysis. This review illustrates
recent applications of CE in pharmaceutical analysis (2005–present).
The history, principles, instruments, and conventional modes
of CE are briefly described. Applications for drug analysis by
various techniques of CE are presented in six tables: capillary
zone electrophoresis (CZE) (Table I), micellar electrokinetic
chromatography (MEKC) and microemulsion electrokinetic chromatography
(MEEKC) (Table II), non-aqueous CE (NACE) (Table III), chiral
CE (Table IV), CE–mass spectrometry (MS) microchip CE (Table
V), and multiplexed CE (MCE) (Table VI).
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