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Published:Journal of Chromatographic Science,
ISSN 0021-9665 Volume 44,
Number 10, November/December 2006, pp.634-638
Thiophilic Interaction Chromatography of Human
Transferrins
Thamarapu Srikrishnan, James T. MacKenzie, and
Eugene Sulkowski
Department of Cancer Biology, Roswell Park Cancer Institute, Buffalo,
New York 14263
Lactoferrin and serum transferrin, the iron-binding
proteins, are widely distributed in biological fluids. Transferrins
have many biological functions: anti-bacterial, anti-inflammatory,
and immunoregulatory. A facile monitoring of the concentration
of transferrins in biological fluids may have medical relevance.
Thiophilic-interaction chromatography of transferrins may provide
an efficient means for their quantitation in serum.
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