Published:Journal of Chromatographic Science,
ISSN 0021-9665Volume
44, Number 4, April 2006, pp. 187-192
Analysis of Residual Products in Triethylbenzylammonium Chloride
by HPLC. Study of the Retention Mechanism
M.C. Prieto-Blanco[1], P. López-Mahía[1,2], and
D. Prada-Rodríguez[1,2]
[1]Deptartment Analytical Chemistry, University of A Coruña. Campus A
Zapateira s/n, E-15071, A Coruña and [2]University Institute of Environment,
University of A Coruña, Pazo de Lóngora, Liáns-Oleiros,
A Coruña 15179, Spain
The control of industrial products for minimization of their impact
on the environment and human health requires the development of specific analysis
methods. Information provided by these methods about toxic components, by-products,
and other derivatives may also be useful to reduce the possible impact of industrial
products. The studied compound in this paper, triethylbenzylammonium chloride
(TEBA), is mainly used in industrial synthesis. This quaternary compound and
its residual products coming from quaternization reaction (benzyl chloride,
benzaldehyde, and benzyl alcohol) are analyzed by HPLC. The separation is based
on control of the silanophilic contribution to TEBA retention because of the
quaternary nature of this compound. The effect of the three buffers (sodium
acetate, ammonium acetate, and sodium formate) and their concentrations in the
chromatographic behavior of the quaternary compound is examined. The buffer
cation and anion regulate TEBA retention. Also, the concentration of the quaternary
compound is another parameter that had influence in some aspects of its chromatographic
behavior (e.g., retention and symmetry). The proposed method is applied to TEBA
synthesis along, with the formation and removal of impurities with the results
compared with those obtained for the quaternary compound benzalkonium chloride.
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