|
Published:Journal of Chromatographic Science,
ISSN 0021-9665Volume
39, Number 10, October 2001, pp. 187-189
Feasibility of Enhancing High-Performance Liquid Chromatography
Using Microwave Radiation
Mark A. Stone and Larry T. Taylor*
Department of Chemistry, Virginia Tech, Blacksburg, VA 24061-0212
High-performance liquid chromatography (HPLC) is the most versatile
of the chromatographic techniques because it is applicable to a wide variety
of analytes. Unfortunately, liquid mobile phases have relatively low diffusivities.
A novel approach is presented for increasing the diffusivity of a liquid mobile
phase. The method advocated in this study is the first process that has been
described by which it is possible to increase the diffusivity of a liquid while
having essentially no effect on other physical properties of the liquid, such
as the temperature or solvating power. It is demonstrated that it is possible
to sharpen peaks, in an HPLC separation, by the application of microwave radiation.
Reproduction
of editorial content of this journal is prohibited without publisher’s
permission.
This
article is available in its entirety by fax for $40.00.
Visa, MasterCard & Amex accepted. To
order electronically
click here
or call: 847-647-2900 ext. 1323
or fax request to: 847-647-1155.
To order multiple copies click here.
Please
indicate JCS volume and issue along with
page numbers. |
Site Map: Home
| Current Issue | Subscribe
| Back Issues | About
Us | Meetings | Advertising
|
| Books for Sale | For
the Author | Links | Supplier
Info | Search | |
