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Published:Journal of Chromatographic Science,
ISSN 0021-9665Volume
40, Number 5, May/June 2002, pp. 234-247
Theoretical and Practical Aspects of Fast Gas Chromatography
and Method Translation
Matthew S. Klee
Agilent Technologies, Inc., 2850 Centerville Rd., Wilmington, DE 19808
Leonid M. Blumberg
Fast GC Consulting, P.0. Box 585, Hockessin, DE 19707
Interest in the development and implementation of fast gas chromatography
(GC) methods continues to increase. Fast GC method development and validation
can be simplified and more successful if a few key theoretical and practical
concepts are kept in mind. Key concepts such as speed-optimized flow rate, optimal
temperature-program rate, sample capacity, “cut the column”, and principles
of method translation are discussed.
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